Description
NAD+ 500mg
NAD+ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme found in every living cell, playing a central role in cellular metabolism, mitochondrial function research, and cellular signaling pathways. NAD+ has been the subject of extensive cellular and biochemical research literature, particularly in the fields of mitochondrial biology, sirtuin enzymology, and cellular aging research.
Each vial contains 500mg of lyophilized NAD+ in a sealed 10mL glass vial, verified through Mile High Compounds’ three-tier quality protocol: 7x independent third-party analytical testing, 4-vial batch conformity verification, and comprehensive heavy metal screening.
Product Specifications
- Compound: NAD+ (Nicotinamide Adenine Dinucleotide)
- Class: Naturally occurring coenzyme / dinucleotide
- Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
- Molecular Weight: ~663 Da
- Form: Lyophilized powder
- Vial Size: 500mg in 10mL glass vial
- Purity: 99%+ verified by HPLC and mass spectrometry (See COAs)
Research Background
NAD+ is a fundamental coenzyme involved in cellular electron transfer reactions and serves as a substrate for numerous enzymatic processes. NAD+ has been investigated in research literature across several scientific contexts:
- Mitochondrial biology research — investigations into NAD+ involvement in oxidative phosphorylation, electron transport chain function, and cellular energy production pathways
- Sirtuin enzymology — extensive research on NAD+-dependent sirtuin proteins (SIRT1-SIRT7) and their roles in cellular regulatory pathways
- PARP enzymology research — studies examining poly(ADP-ribose) polymerase enzymes and their NAD+-consuming reactions in cellular biology
- CD38 and NAD+ metabolism research — investigations into NAD+ degradation pathways and cellular NAD+ homeostasis
- Cellular aging research — research literature examining NAD+ levels across cellular aging models and tissue contexts
- Cellular redox biology — research on NAD+/NADH ratio dynamics in cellular metabolic states
NAD+ research has expanded substantially over the past two decades, with peer-reviewed literature published across high-impact journals including Cell, Nature, and Science. Foundational research is available through PubMed (pubmed.ncbi.nlm.nih.gov) and the National Institutes of Health’s PMC database (pmc.ncbi.nlm.nih.gov), where researchers can access peer-reviewed studies on NAD+ cellular biology, including work by leading research groups including Sinclair et al., Imai et al., and Verdin et al. on cellular NAD+ biology.
Analytical Verification
Every batch undergoes Mile High Compounds’ comprehensive analytical protocol:
- High-Performance Liquid Chromatography (HPLC) for purity quantification
- Mass Spectrometry (MS) for molecular weight and identity confirmation
- 14-day sterility testing
- Endotoxin analysis
- 4-vial batch conformity verification — statistically robust consistency testing across each production batch, exceeding the industry-standard single-vial sampling approach
- Heavy metal screening for lead, arsenic, cadmium, mercury, and additional trace metals
- Container and seal integrity verification
Batch-specific Certificates of Analysis (COAs) accompany every order, documenting full testing results across all verification protocols.
Reconstitution and Storage
- Lyophilized storage: Cool, dry location away from direct light; -20°C for long-term stability
- Post-reconstitution: Refrigerate at 2-8°C, protect from light and oxygen exposure
- Reconstituted use window: 14 days for optimal research integrity due to NAD+ susceptibility to degradation
- Avoid: Repeated freeze-thaw cycles, prolonged light exposure, and oxidative conditions
Quality Standards
Mile High Compounds maintains a rigorous quality control framework across all research compounds. Our multi-layered testing protocol provides researchers with verified, high-purity reference materials supported by complete analytical documentation.
- 7x independent third-party testing per batch
- 4-vial batch conformity verification
- Heavy metal screening for trace contaminant analysis
- cGMP-compliant manufacturing
- Full analytical traceability
- Same-day shipping for orders placed before 3PM MST
Terms of Sale
This product is supplied for in vitro laboratory research only and has not been evaluated by the U.S. Food and Drug Administration. By purchasing, the buyer confirms they are 21 or older, a qualified research professional or institution, and will not use this material for human consumption, veterinary use, or any in vivo application. Mile High Compounds assumes no liability for misuse or off-label application.
About Mile High Compounds
Colorado-based research compound supplier specializing in high-purity reference materials for laboratory applications. Every batch undergoes our three-tier quality protocol: 7x independent third-party analytical verification, 4-vial batch conformity testing, and comprehensive heavy metal screening — manufactured in cGMP-compliant facilities.
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