Sermorelin

Sermorelin 10mg

Sermorelin is a synthetic 29-amino acid peptide representing the biologically active N-terminal fragment of human growth hormone-releasing hormone (GHRH 1-29). Composed of the first 29 amino acids of native human GHRH, Sermorelin has been the subject of extensive cellular and biochemical research literature examining GHRH receptor biology, pituitary cellular signaling, and peptide structure-activity relationships.

Each vial contains 10mg of lyophilized Sermorelin in a sealed 3mL glass vial, verified through Mile High Compounds’ three-tier quality protocol: 7x independent third-party analytical testing, 4-vial batch conformity verification, and comprehensive heavy metal screening.

Product Specifications

• Compound: Sermorelin (GHRH 1-29)
• Class: Synthetic GHRH analog, 29 amino acids
• Origin: Active N-terminal fragment of human GHRH
• Molecular Weight: ~3358 Da
• Form: Lyophilized powder
• Vial Size: 10mg in 3mL glass vial
• Purity: 99%+ verified by HPLC and mass spectrometry (See COAs)

Research Background

Sermorelin has been investigated in research literature across several scientific contexts:

• GHRH receptor pharmacology — investigations into receptor binding kinetics, signal transduction, and cellular response mechanisms in pituitary cell models
• GHRH structure-activity relationships — comparative research on the GHRH 1-29 fragment versus full-length GHRH (1-44), examining which structural elements drive receptor binding
• Pituitary cellular biology — studies examining anterior pituitary cell responsiveness to native and synthetic GHRH peptides
• Peptide truncation research — analytical studies on minimal active sequences in GHRH biology
• Comparative GHRH analog research — studies positioning Sermorelin alongside other modified GHRH analogs (such as Tesamorelin) in cellular research contexts

Sermorelin is historically significant in peptide research as one of the earliest characterized GHRH analogs, originally identified through fragment analysis of native human GHRH. Foundational research is available through PubMed (pubmed.ncbi.nlm.nih.gov) and the National Institutes of Health’s PMC database (pmc.ncbi.nlm.nih.gov), where researchers can access peer-reviewed studies on GHRH biology and Sermorelin specifically.

Analytical Verification

Every batch undergoes Mile High Compounds’ comprehensive analytical protocol:

• High-Performance Liquid Chromatography (HPLC) for purity quantification
• Mass Spectrometry (MS) for molecular weight and identity confirmation
• 14-day sterility testing
• Endotoxin analysis
• 4-vial batch conformity verification — statistically robust consistency testing across each production batch, exceeding the industry-standard single-vial sampling approach
• Heavy metal screening for lead, arsenic, cadmium, mercury, and additional trace metals
• Container and seal integrity verification

Batch-specific Certificates of Analysis (COAs) accompany every order, documenting full testing results across all verification protocols.

Reconstitution and Storage

• Lyophilized storage: Cool, dry location away from direct light; -20°C for long-term stability
• Post-reconstitution: Refrigerate at 2-8°C, protect from light
• Reconstituted use window: 14 days for optimal research integrity due to GHRH peptide stability characteristics
• Avoid: Repeated freeze-thaw cycles to preserve compound stability and structural integrity

Quality Standards

Mile High Compounds maintains a rigorous quality control framework across all research compounds. Our multi-layered testing protocol provides researchers with verified, high-purity reference materials supported by complete analytical documentation.

• 7x independent third-party testing per batch
• 4-vial batch conformity verification
• Heavy metal screening for trace contaminant analysis
• cGMP-compliant manufacturing
• Full analytical traceability
• Same-day shipping for orders placed before 3PM MST

Terms of Sale

This product is supplied for in vitro laboratory research only and has not been evaluated by the U.S. Food and Drug Administration. By purchasing, the buyer confirms they are 21 or older, a qualified research professional or institution, and will not use this material for human consumption, veterinary use, or any in vivo application. Mile High Compounds assumes no liability for misuse or off-label application.

About Mile High Compounds

Colorado-based research compound supplier specializing in high-purity reference materials for laboratory applications. Every batch undergoes our three-tier quality protocol: 7x independent third-party analytical verification, 4-vial batch conformity testing, and comprehensive heavy metal screening — manufactured in cGMP-compliant facilities.

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