IGF-1 LR3

IGF-1 LR3 1mg

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is a synthetic analog of human Insulin-like Growth Factor-1 modified with two structural changes from native IGF-1: an arginine substitution at position 3 and an N-terminal extension of 13 amino acids. These modifications significantly extend the peptide’s half-life and reduce binding affinity to IGF-binding proteins compared to native IGF-1. As a research peptide, IGF-1 LR3 has been studied in cellular biology and biochemical research literature examining IGF receptor pharmacology and peptide stability engineering.

Each vial contains 1mg of lyophilized IGF-1 LR3 in a sealed 3mL glass vial, verified through Mile High Compounds’ three-tier quality protocol: 7x independent third-party analytical testing, 4-vial batch conformity verification, and comprehensive heavy metal screening.

Product Specifications

• Compound: IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1)
• Class: Synthetic IGF-1 analog, 83 amino acids
• Modifications: Arg³ substitution and 13-amino acid N-terminal extension
• Molecular Weight: ~9100 Da
• Form: Lyophilized powder
• Vial Size: 1mg in 3mL glass vial
• Purity: 99%+ verified by HPLC and mass spectrometry (See COAs)

Research Context

IGF-1 LR3 is utilized in research applications involving peptide chemistry, IGF receptor pharmacology, and cellular research applications. As a long-acting IGF-1 analog, the compound represents a research subject in the broader field of peptide stability engineering — specifically the use of structural modifications including N-terminal extension and amino acid substitution strategies to extend peptide half-life and modify peptide-binding protein interactions compared to native IGF-1 sequences.

This compound is supplied exclusively for in vitro research and laboratory investigation by qualified researchers in appropriate research environments.

Analytical Verification

Every batch undergoes Mile High Compounds’ comprehensive analytical protocol:

• High-Performance Liquid Chromatography (HPLC) for purity quantification
• Mass Spectrometry (MS) for molecular weight and identity confirmation
• 14-day sterility testing
• Endotoxin analysis
• 4-vial batch conformity verification — statistically robust consistency testing across each production batch, exceeding the industry-standard single-vial sampling approach
• Heavy metal screening for lead, arsenic, cadmium, mercury, and additional trace metals
• Container and seal integrity verification

Batch-specific Certificates of Analysis (COAs) accompany every order, documenting full testing results across all verification protocols.

Reconstitution and Storage

• Lyophilized storage: Cool, dry location away from direct light; -20°C for long-term stability
• Post-reconstitution: Refrigerate at 2-8°C, protect from light
• Reconstituted use window: 30 days for optimal research integrity
• Avoid: Repeated freeze-thaw cycles to preserve compound stability and structural integrity

Quality Standards

Mile High Compounds maintains a rigorous quality control framework across all research compounds. Our multi-layered testing protocol provides researchers with verified, high-purity reference materials supported by complete analytical documentation.

• 7x independent third-party testing per batch
• 4-vial batch conformity verification
• Heavy metal screening for trace contaminant analysis
• cGMP-compliant manufacturing
• Full analytical traceability
• Same-day shipping for orders placed before 3PM MST

Terms of Sale

This product is supplied for in vitro laboratory research only and has not been evaluated by the U.S. Food and Drug Administration. By purchasing, the buyer confirms they are 21 or older, a qualified research professional or institution, and will not use this material for human consumption, veterinary use, or any in vivo application. Mile High Compounds assumes no liability for misuse or off-label application.

About Mile High Compounds

Colorado-based research compound supplier specializing in high-purity reference materials for laboratory applications. Every batch undergoes our three-tier quality protocol: 7x independent third-party analytical verification, 4-vial batch conformity testing, and comprehensive heavy metal screening — manufactured in cGMP-compliant facilities.

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