Description
CJC-1295 with DAC 5mg
CJC-1295 with DAC is a synthetic long-acting peptide analog of growth hormone-releasing hormone (GHRH), structurally modified with a Drug Affinity Complex (DAC) — a maleimidopropionic acid (MPA) group that enables covalent binding to serum albumin, substantially extending the peptide’s half-life compared to native GHRH sequences. As a synthetic research peptide, CJC-1295 with DAC has been studied in cellular research literature examining GHRH receptor pharmacology and peptide stability engineering through albumin-binding strategies.
Each vial contains 5mg of lyophilized CJC-1295 with DAC in a sealed 3mL glass vial, verified through Mile High Compounds’ three-tier quality protocol: 7x independent third-party analytical testing, 4-vial batch conformity verification, and comprehensive heavy metal screening.
Product Specifications
- Compound: CJC-1295 with DAC
- Class: Synthetic GHRH analog with albumin-binding modification
- Origin: Modified GHRH (1-29) analog with N-terminal Drug Affinity Complex
- Molecular Weight: ~3647 Da
- Form: Lyophilized powder
- Vial Size: 5mg in 3mL glass vial
- Purity: 99%+ verified by HPLC and mass spectrometry (See COAs)
Research Background
CJC-1295 with DAC has been investigated in research literature across several scientific contexts:
- GHRH receptor pharmacology — investigations into receptor binding kinetics, signal transduction, and cellular response mechanisms in pituitary cell models
- Albumin-binding peptide research — studies examining how covalent serum albumin binding via maleimidopropionic acid modification affects peptide half-life, distribution, and stability properties
- Peptide half-life engineering — analytical chemistry research on extended-duration peptide analogs and the structural modifications that enable prolonged biological activity
- Comparative GHRH analog research — studies positioning CJC-1295 with DAC alongside other modified GHRH peptides (including Sermorelin and Tesamorelin) in cellular research contexts
- Structure-activity relationships — peptide chemistry research on how DAC modification affects receptor binding affinity compared to non-modified GHRH analogs
- Cellular signaling pathway research — investigations into GHRH receptor activation and downstream cellular signaling cascades
CJC-1295 with DAC was originally developed by ConjuChem Biotechnologies as part of their broader Drug Affinity Complex peptide research platform, which utilized albumin-binding chemistry to extend peptide half-life across multiple research compound development programs. The DAC technology represents a notable case study in peptide engineering aimed at solving the inherent stability limitations of short-half-life peptides like native GHRH. Foundational research is available through PubMed (pubmed.ncbi.nlm.nih.gov) and the National Institutes of Health’s PMC database (pmc.ncbi.nlm.nih.gov), where researchers can access peer-reviewed studies on CJC-1295, the DAC modification platform, and GHRH analog research.
Analytical Verification
Every batch undergoes Mile High Compounds’ comprehensive analytical protocol:
- High-Performance Liquid Chromatography (HPLC) for purity quantification
- Mass Spectrometry (MS) for molecular weight and identity confirmation
- 14-day sterility testing
- Endotoxin analysis
- 4-vial batch conformity verification — statistically robust consistency testing across each production batch, exceeding the industry-standard single-vial sampling approach
- Heavy metal screening for lead, arsenic, cadmium, mercury, and additional trace metals
- Container and seal integrity verification
Batch-specific Certificates of Analysis (COAs) accompany every order, documenting full testing results across all verification protocols.
Reconstitution and Storage
- Lyophilized storage: Cool, dry location away from direct light; -20°C for long-term stability
- Post-reconstitution: Refrigerate at 2-8°C, protect from light
- Reconstituted use window: 30 days for optimal research integrity
- Avoid: Repeated freeze-thaw cycles to preserve compound stability and structural integrity
Quality Standards
Mile High Compounds maintains a rigorous quality control framework across all research compounds. Our multi-layered testing protocol provides researchers with verified, high-purity reference materials supported by complete analytical documentation.
- 7x independent third-party testing per batch
- 4-vial batch conformity verification
- Heavy metal screening for trace contaminant analysis
- cGMP-compliant manufacturing
- Full analytical traceability
- Same-day shipping for orders placed before 3PM MST
Terms of Sale
This product is supplied for in vitro laboratory research only and has not been evaluated by the U.S. Food and Drug Administration. By purchasing, the buyer confirms they are 21 or older, a qualified research professional or institution, and will not use this material for human consumption, veterinary use, or any in vivo application. Mile High Compounds assumes no liability for misuse or off-label application.
About Mile High Compounds
Colorado-based research compound supplier specializing in high-purity reference materials for laboratory applications. Every batch undergoes our three-tier quality protocol: 7x independent third-party analytical verification, 4-vial batch conformity testing, and comprehensive heavy metal screening — manufactured in cGMP-compliant facilities.
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