AHK-Cu

AHK-Cu (Alanyl-L-Histidyl-L-Lysine Copper) is a synthetic copper-binding tripeptide complex consisting of alanine, histidine, and lysine bound to a copper(II) ion. Structurally related to GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper) with alanine substituted for glycine at the N-terminus, AHK-Cu has been studied in cellular biology and biochemical research literature examining copper-binding peptide chemistry, cellular signaling pathways, and tissue research applications.

Each vial contains 100mg of lyophilized AHK-Cu in a sealed 5mL glass vial, verified through Mile High Compounds’ three-tier quality protocol: 7x independent third-party analytical testing, 4-vial batch conformity verification, and comprehensive heavy metal screening.

Product Specifications

• Compound: AHK-Cu (Alanyl-L-Histidyl-L-Lysine Copper)
• Class: Synthetic copper-binding tripeptide complex
• Sequence: Ala-His-Lys
• Molecular Weight: ~354 Da (tripeptide); ~417 Da (copper complex)
• Form: Lyophilized powder
• Vial Size: 100mg in 5mL glass vial
• Purity: 99%+ verified by HPLC and mass spectrometry (See COAs)

Research Background

AHK-Cu has been investigated in research literature across several scientific contexts:

• Copper-binding peptide chemistry — analytical chemistry research on AHK’s selective copper binding properties and structural relationships to other copper-binding peptides
• Tissue biology research — investigations into peptide-copper complex effects on cellular signaling pathways in tissue research models
• Comparative copper-binding peptide research — analytical studies positioning AHK-Cu alongside GHK-Cu and other naturally occurring copper-binding peptides in cellular research contexts
• Cellular signaling pathway research — investigations into AHK-Cu’s interactions with cellular receptor systems and downstream signaling cascades
• Peptide chemistry research — analytical chemistry studies on tripeptide structure-activity relationships and copper coordination chemistry

AHK-Cu represents a structural variant within the broader category of copper-binding tripeptide research compounds, structurally related to GHK-Cu and offering comparative research opportunities in copper coordination chemistry. Foundational research is available through PubMed (pubmed.ncbi.nlm.nih.gov) and the National Institutes of Health’s PMC database (pmc.ncbi.nlm.nih.gov), where researchers can access peer-reviewed studies on copper-binding peptide research.

Analytical Verification

Every batch undergoes Mile High Compounds’ comprehensive analytical protocol:

• High-Performance Liquid Chromatography (HPLC) for purity quantification
• Mass Spectrometry (MS) for molecular weight and identity confirmation
• 14-day sterility testing
• Endotoxin analysis
• 4-vial batch conformity verification — statistically robust consistency testing across each production batch, exceeding the industry-standard single-vial sampling approach
• Heavy metal screening for lead, arsenic, cadmium, mercury, and additional trace metals
• Container and seal integrity verification

Batch-specific Certificates of Analysis (COAs) accompany every order, documenting full testing results across all verification protocols.

Reconstitution and Storage

• Lyophilized storage: Cool, dry location away from direct light; -20°C for long-term stability
• Post-reconstitution: Refrigerate at 2-8°C, protect from light
• Reconstituted use window: 30 days for optimal research integrity
• Avoid: Repeated freeze-thaw cycles to preserve compound stability and structural integrity

Quality Standards

Mile High Compounds maintains a rigorous quality control framework across all research compounds. Our multi-layered testing protocol provides researchers with verified, high-purity reference materials supported by complete analytical documentation.

• 7x independent third-party testing per batch
• 4-vial batch conformity verification
• Heavy metal screening for trace contaminant analysis
• cGMP-compliant manufacturing
• Full analytical traceability
• Same-day shipping for orders placed before 3PM MST

Terms of Sale

This product is supplied for in vitro laboratory research only and has not been evaluated by the U.S. Food and Drug Administration. By purchasing, the buyer confirms they are 21 or older, a qualified research professional or institution, and will not use this material for human consumption, veterinary use, or any in vivo application. Mile High Compounds assumes no liability for misuse or off-label application.

About Mile High Compounds

Colorado-based research compound supplier specializing in high-purity reference materials for laboratory applications. Every batch undergoes our three-tier quality protocol: 7x independent third-party analytical verification, 4-vial batch conformity testing, and comprehensive heavy metal screening — manufactured in cGMP-compliant facilities.

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